Topoisomerase II inhibitors, such as mitoxantrone, have been linked to the event of secondary acute myeloid leukemia and myelosuppression. General Therapy with mitoxantrone needs to be accompanied by near and frequent checking of hematologic and chemical laboratory parameters, and also Regular cl

In distinction to neurodegerative disorders and cancer, the contribution of TG2 activity to celiac sprue pathogenesis has long been fairly nicely established. The deamidation of unique glutamine residues qualified by TG2 in gluten peptides has long been revealed to reinforce peptide binding to your